In Henoch-Schonlein purpura, which extra-cutaneous symptom is commonly observed?

In Henoch-Schonlein purpura, which extra-cutaneous symptom is commonly observed?

• A. Headache
• B. Abdominal pain
• C. Rash on palms
• D. Seizures

Answer: (B)

In Henoch-Schönlein purpura, the disease is an IgA-mediated small-vessel vasculitis that commonly involves the skin, joints, gut, and kidneys. While the skin shows palpable purpura, the gut is frequently affected by vasculitis, leading to abdominal pain. This abdominal pain is often colicky and can be accompanied by vomiting or even GI bleeding, and in some cases may complicate into issues like intussusception. That makes abdominal pain a very typical extra-cutaneous symptom in this condition. Headache and seizures don’t fit the pattern of HSP and aren’t characteristic features. A rash on the palms is also atypical because the classic purpuric rash in HSP appears on the buttocks and legs rather than on the palms.

In Henoch-Schönlein purpura, the disease is an IgA-mediated small-vessel vasculitis that commonly involves the skin, joints, gut, and kidneys. While the skin shows palpable purpura, the gut is frequently affected by vasculitis, leading to abdominal pain. This abdominal pain is often colicky and can be accompanied by vomiting or even GI bleeding, and in some cases may complicate into issues like intussusception. That makes abdominal pain a very typical extra-cutaneous symptom in this condition.

Headache and seizures don’t fit the pattern of HSP and aren’t characteristic features. A rash on the palms is also atypical because the classic purpuric rash in HSP appears on the buttocks and legs rather than on the palms.